Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald—Hartwig Coupling |
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| Authors: | Joana F. Campos Manon Cailler Remi Claudel Benjamin Prot Thierry Besson Sabine Berteina-Raboin |
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| Affiliation: | 1.Institut de Chimie Organique et Analytique (ICOA), Université d’Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France; (J.F.C.); (M.C.); (R.C.); (B.P.);2.Normandie Univ., UNIROUEN, INSA Rouen, CNRS, COBRA UMR 6014, 76000 Rouen, France; |
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| Abstract: | The development of new and greener approaches to organic synthesis has been a trend in recent years. Continuing the latest publications of our team, in this work, we demonstrate the efficiency of three solvents: eucalyptol (1,8-cineole), cyclopentyl methyl ether (CPME), and 2-methyltetrahydrofuran (2-MeTHF) for the synthesis of O,S,N-heterocyclic compounds. |
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| Keywords: | eucalyptol cyclopentyl methyl ether 2-methyltetrahydrofuran O S N-heterocycles greener methodology green solvent |
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