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Nanomaterials for Biomedical Applications: Production,Characterisations, Recent Trends and Difficulties
Authors:Mostafa Mabrouk  Diganta B Das  Zeinab A Salem  Hanan H Beherei
Institution:1.Refractories, Ceramics and Building Materials Department, National Research Centre, 33El Bohouth St (former EL Tahrir St), Dokki, Giza P.O. 12622, Egypt;2.Department of Chemical Engineering, Loughborough University, Loughborough LE113TU, Leicestershire, UK;3.Department of Oral Biology, Faculty of Dentistry, Cairo University, Giza P.O. 12613, Egypt;4.Faculty of Oral and Dental Medicine, Ahram Canadian University, 6 October City P.O. 12573, Egypt
Abstract:Designing of nanomaterials has now become a top-priority research goal with a view to developing specific applications in the biomedical fields. In fact, the recent trends in the literature show that there is a lack of in-depth reviews that specifically highlight the current knowledge based on the design and production of nanomaterials. Considerations of size, shape, surface charge and microstructures are important factors in this regard as they affect the performance of nanoparticles (NPs). These parameters are also found to be dependent on their synthesis methods. The characterisation techniques that have been used for the investigation of these nanomaterials are relatively different in their concepts, sample preparation methods and obtained results. Consequently, this review article aims to carry out an in-depth discussion on the recent trends on nanomaterials for biomedical engineering, with a particular emphasis on the choices of the nanomaterials, preparation methods/instruments and characterisations techniques used for designing of nanomaterials. Key applications of these nanomaterials, such as tissue regeneration, medication delivery and wound healing, are also discussed briefly. Covering this knowledge gap will result in a better understanding of the role of nanomaterial design and subsequent larger-scale applications in terms of both its potential and difficulties.
Keywords:tissue regeneration  drug delivery systems  preparation methods/tools  characterisation techniques
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