Total synthesis and absolute configuration of otteliones A and B, novel and potent antitumor agents from a freshwater plant |
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Authors: | Araki Hiroshi Inoue Munenori Katoh Tadashi |
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Institution: | Department of Electronic Chemistry, Tokyo Institute of Technology, Nagatsuta, Yokohama 226-8502, Japan. |
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Abstract: | reaction: see text] The first enantioselective total synthesis of otteliones A and B, biologically important and structurally novel natural products, has been successfully achieved. This total synthesis fully confirms the absolute configuration of these natural products. |
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