Synthesis,physico-chemical and DNA interactive studies of l-tryptophan based mononuclear Schiff base complexes of first transition metal series |
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| Authors: | Nida Shahid Naushaba Sami Mohammad Shakir Mohammad Aatif |
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| Institution: | 1. Division of Inorganic Chemistry, Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India;2. Departmet of Biochemistry, Aligarh Muslim University, Aligarh 202002 India |
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| Abstract: | l-Tryptophan derived Schiff base ligand and its complexes of the type, ML(H2O)2]·H2O M?=?Co(II), Ni(II), Zn(II)] and CuL] have been synthesized and characterized on the basis of results obtained from elemental analysis, conductivity measurements, ESI-Mass spectral studies, FT-IR, 1H and 13C NMR, UV–Vis spectroscopy and magnetic moment data. The synthesized complexes were subjected to thermogravimetric analysis to study their decomposition pattern and stability. The fluorescence and viscosity measurements reveal that complexes have significant CT-DNA binding. However, upon comparing the DNA binding analyses, Cu(II) complex exhibited significant binding affinity. |
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| Keywords: | Spectroscopic studies DNA-binding |
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