Glassy Carbon Paste Electrodes for the Determination of Fructosyl Valine |
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Authors: | Hui‐Ching Chien Tse‐Chuan Chou |
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Institution: | 1. Department of Chemical Engineering, National Cheng Kung University, Tainan 701, Taiwan;2. Department of Chemical Engineering, Tatung University, Taipei 104, Taiwan |
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Abstract: | Nearly 200 million people worldwide have type‐2 diabetes. Glucose sensors are routinely used for diagnosis; however, the relative amount of glycosylated hemoglobin (HbA1c) may be a better marker. A working electrode made from bare glassy carbon paste was used for sensing fructosyl valine (Fru‐Val), a component of HbA1c. Amperometric measurements revealed a linear relationship between Fru‐Val concentration and the sensing current. The square correlation coefficient and the sensitivity were 0.999 and 5.26 μA mM?1, respectively. The minimum detection limit was less than 0.05 mM. |
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Keywords: | Glassy carbon paste electrode (GCPE) Fructosyl valine (Fru‐Val) Glycosylated hemoglobin (HbA1c) Biosensors |
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