Genetic diversity and haplotype structure of 24 Y‐chromosomal STR in Chinese Hui ethnic group and its genetic relationships with other populations |
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| Authors: | Bo‐Feng Zhu Yu‐Dang Zhang Wen‐Juan Liu Hao‐Tian Meng Guo‐Lian Yuan Zhe Lv Nan Dong Qiong Li Chun‐hua Yang Yu‐Hong Zhang Yin‐Ling Hou Li Qian Shuan‐Liang Fan Peng Xu |
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| Institution: | 1. Shanghai Key Laboratory of Forensic Sciences, Institute of Forensic Sciences, Ministry of Justice, Shanghai, P. R. China;2. Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China;3. Scientific Research and Experiment Center, The Second Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China;4. Criminal Police Detachment of Guyuan City Public Security Bureau, Guyuan, P. R. China;5. Criminal Police Detachment of Nantong City Public Security Bureau, Nantong, P. R. China;6. Criminal Police Detachment of Xuzhou City Public Security Bureau, Xuzhou, P. R. China;7. Criminal Police Detachment of Huaian City Public Security Bureau, Huaian, P. R. China;8. Department of Joint Surgery, Xi'an Hong‐hui Hospital, Xi'an, P. R. China;9. Department of Joint Surgery, Hong‐Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, P. R. China |
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| Abstract: | In the present study, 24 Y‐chromosomal short tandem repeat (Y‐STR) loci were analyzed in 115 unrelated Hui male individuals from Haiyuan county or Tongxin county, Ningxia Hui Autonomous Region, China, to evaluate the forensic application of the 24 STR loci and to analyze interpopulation differentiations by making comparisons between the Hui group data and previously published data of other 13 populations. A total of 115 different haplotypes were observed on these 24 Y‐STR loci. The gene diversities ranged from 0.4049 (DYS437) to 0.9729 (DYS385a, b). The overall haplotype diversity was 1 at AGCU 24 Y‐STR loci level, while the values were reduced to 0.999237, 0.996949, and 0.996644 at the Y‐filer 17 loci, 11 Y‐STR loci of extended haplotype and 9 Y‐STR loci of minimal haplotype levels, respectively; whereas, haplotype diversity for additional 7 loci (not included in Y‐filer 17 loci) was 0.995271. The pairwise FST, multidimensional scaling plot and neighbor‐joining tree indicated the Hui group had the closest genetic relationship with Sala in the paternal lineage in the present study. In summary, the results in our study indicated the 24 Y‐STRs had a high level of polymorphism in Hui group and hence could be a powerful tool for forensic application and population genetic study. |
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| Keywords: | AGCU Y24 STR Chinese Hui group Haplotype structure Y‐chromosomal STR |
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