Determination of Norepinephrine Alone and in the Presence of Ascorbic and Uric Acids Using a Gold Electrode Modified with Gold Nanoparticles and Self‐Assembled Layers of meso‐2,3‐Dimercaptosuccinic Acid |
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Authors: | Teresa Łuczak |
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Affiliation: | Faculty of Chemistry, Adam Mickiewicz University, Umultowska 89b, 61–614 Poznań, Poland fax: +48?61?86558008 |
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Abstract: | This paper reports on the modification of gold electrodes with self‐assembled layers (SAMs) composed of meso‐2,3‐dimercaptosuccinic acid, cysteamine and gold nanoparticles, respectively and their application to quantitative determination of norepinephrine alone and in the presence of ascorbic and uric acids in solution at pH 7. The modification was carried out on two kinds of templates: a bare gold electrode (2D electrode) and a gold electrode coated in the first step with gold nanoparticles (3D electrode). Cyclic voltammograms reveal an enhancement of the norepinephrine electrooxidation in comparison to a bare, (non‐modified) gold electrode. The oxidation peaks for norepinephrine, ascorbic acid and uric acid have a peak‐to‐peak separation that enables their selective determination even in a complex mixture. |
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Keywords: | Gold electrodes Gold nanoparticles Self‐assembled layers Neurotransmitters Norepinephrine |
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