Voltammetric Analysis of Naproxen in Graphite Electrodes and Its Determination in Pharmaceutical Samples |
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| Authors: | G Y Aguilar‐Lira G A Álvarez Romero A Rojas‐Hernández M E Páez‐Hernández J A Rodríguez‐Ávila M A Romero‐Romo |
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| Institution: | 1. Universidad Autónoma del Estado de Hidalgo, área Académica de Química, Carretera Pachuca‐Tulancingo km 4.5, 42184 Mineral de la Reforma, Hidalgo;2. Universidad Autónoma Metropolitana unidad Iztapalapa, área de Química Analítica, Av, Michoacán y Purísima s/n Col. Vicentina, C.P. 09340, México D.F.;3. Universidad Autónoma Metropolitana‐Azcapotzalco, área Ingeniería de Materiales, Av. San Pablo 180, Col Reynosa Tamaulipas, C.P. 02200, México, D.F. |
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| Abstract: | The present work discuses new findings in the electrochemistry of naproxen over graphite electrodes. This new approach, allows the proposal of a simple and competitive low‐cost method to carry out naproxen’s voltammetric quantification. Naproxen’s indirect quantification through an adsorption anodic wave was performed at a graphite bar electrode using differential pulse voltammetry. An anodic current maximum was recorded at a potential of ?0.3 V referred to a saturated Ag/AgCl reference electrode. The calibration plot having a correlation coefficient of 0.990, sensibility of 4.19±0.62 µA cm3 µg?1, with detection and quantification limits of 0.68 and 3.3 µg cm?3, respectively. |
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| Keywords: | Differential pulse voltammetry Naproxen Pharmaceutical samples Graphite electrode |
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