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A Glassy Carbon Electrode Modified with LangmuirBlodgett Film Composed of DNA and Polyaniline for the Sensitive Determination of Salbutamol |
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| Authors: | Lina Zou Yinfeng Li Shaokui Cao Baoxian Ye |
| Affiliation: | 1. College of Chemistry and Molecular Engineering and School of Material Science & Engineering, Zhengzhou University, Zhengzhou 450001, P.R. China tel: +86?0371?67781757, +86?0371?67763561 fax: +86?0371?67763654, +86?0371?67763523;2. School of Chemical and Material Engineering, Henan University of Urban Construction, Pingdingshan 467036, P.R. China |
| Abstract: | A composite Langmuir? Blodgett film prepared from DNA and polyaniline was deposited on the surface of a glassy carbon electrode (GCE) to give a new voltammetric sensor for the β2‐agonist salbutamol (SAL). Cyclic voltammetry and electrochemical impedance spectroscopy were employed to study the characteristic of the modified electrode. The electrochemistry of SAL at the modified electrode was investigated at pH 6.8 by cyclic voltammetry and differential pulse anodic voltammetry. The oxidation of SAL at this electrode is an adsorption‐controlled irreversible process. A sensitive electroanalytical method for determination of SAL was worked out that displays high precision and good reproducibility. The method was applied to quantify SAL in tablets with satisfactory results. |
| Keywords: | DNA Polyaniline Langmuir Blodgett film Voltammetric sensor Salbutamol |