Electrochemical Sensors for Nitric Oxide Detection in Biological Applications |
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| Authors: | Tailin Xu Nikki Scafa Li‐Ping Xu Lei Su Chenzhong Li Shufeng Zhou Yang Liu Xueji Zhang |
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| Institution: | 1. Research Center for Bioengineering and Sensing Technology, University of Science and Technology Beijing, Beijing 100083, P.?R. China;2. World Precision Instruments, Inc, Sarasota, FL 34240‐9258, USA;3. Department of Biomedical Engineering, Florida International University, Miami, Fl 33174, USA;4. School of Pharmacy, University of South Florida, Tampa, Fl 33612, USA;5. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P.?R. China |
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| Abstract: | Nitric oxide (NO) plays an important role in physiological processes and it has been confirmed some human diseases are related to its biological function. Electrochemical sensors provide an efficient way to explore the NO function in biological processes. This review details different kinds of electrochemical sensors used for NO concentration detection between 2008 and 2013 together with their application in biological samples. Four commonly used electrodes and different assisted analysis membranes used for contributions towards the development of the novel sensors were summarized. Electrochemical sensors employed to measure NO concentration in a single cell, cell culture, tissue homogenate, organ, in vivo, human being, as well as in plant were also detailed. The trends of developing novel NO sensors were outlooked in the last part. |
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| Keywords: | Nitric oxide sensors Electrochemical sensors Biosensors Fractional exhale nitric oxide (FENO) NIOX‐MINO Ischemia/Reperfusion injury |
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