Tithoniamarin and tithoniamide: a structurally unique isocoumarin dimer and a new ceramide from Tithonia diversifolia |
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Authors: | Yemele Bouberte Meffo Krohn Karsten Hussain Hidayat Dongo Etienne Schulz Barbara Hu Qunxiu |
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Institution: | Department of Organic Chemistry, Faculty of Science, Yaounde University I, PO Box 812, Yaounde, Cameroon. |
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Abstract: | Tithoniamarin (1), a new isocoumarin dimer and a new ceramide, named tithoniamide (2a), have been isolated from Tithonia diversifolia, in addition to the known beta-sitosterol and beta-sitosterol glucopyranoside. The structures were elucidated on the basis of spectroscopic and chemical evidence. Preliminary studies showed that 1 has antifungal and herbicidal activities against Microbotryum violaceum and Chlorella fusca. |
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