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Tithoniamarin and tithoniamide: a structurally unique isocoumarin dimer and a new ceramide from Tithonia diversifolia
Authors:Yemele Bouberte Meffo  Krohn Karsten  Hussain Hidayat  Dongo Etienne  Schulz Barbara  Hu Qunxiu
Institution:Department of Organic Chemistry, Faculty of Science, Yaounde University I, PO Box 812, Yaounde, Cameroon.
Abstract:Tithoniamarin (1), a new isocoumarin dimer and a new ceramide, named tithoniamide (2a), have been isolated from Tithonia diversifolia, in addition to the known beta-sitosterol and beta-sitosterol glucopyranoside. The structures were elucidated on the basis of spectroscopic and chemical evidence. Preliminary studies showed that 1 has antifungal and herbicidal activities against Microbotryum violaceum and Chlorella fusca.
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