Synthesis of Optically Active 2- and 3- Indolylglycine Derivatives and their Oxygen Analogues期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Synthesis of Optically Active 2- and 3- Indolylglycine Derivatives and their Oxygen Analogues

Authors:	Koushik Goswami Indranil Duttagupta Surajit Sinha

Affiliation:	Department of Organic Chemistry, Indian Association for the Cultivation of Science , Jadavpur, Kolkata 700 032, India.

Abstract:	2-Indolylglycine derivative and its oxygen analogue have been synthesized by Sonogashira coupling followed by cyclization in one pot between 2-iodoheteroarenes and ethynyloxazolidinone where 3-indolylglycine derivative and its oxygen analogue have been synthesized from silylated internal alkyne using Larock's heteroannulation as the key reaction.

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