Ionic catch and release oligosaccharide synthesis (ICROS) |
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| Authors: | Tran Anh-Tuan Burden Richard Racys Daugirdas T Galan M Carmen |
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| Institution: | School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK. |
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| Abstract: | A general and efficient chromatography-free ionic-liquid-supported "catch-and-release" strategy for oligosaccharide synthesis (ICROS) is reported. The methodology is compatible with current glycosylation strategies and amenable to protecting group manipulations. A series of β-(1→6) and β-(1→2)-linked glycan structures have been prepared to showcase the versatility of the strategy. |
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