Detection and recognition of cancer cells in vivo |
| |
| Authors: | V.A. Namiot E.A. Kogan |
| |
| Affiliation: | 1. D.V. Skobeltsyn Institute of Nuclear Physics, M.V. Lomonosov Moscow State University, 1(2), Leninskie gory, GSP-1, Moscow 119991, Russian Federation;2. I.M. Setchenov First Moscow State Medical University, Malaya Trubetskaya Str., 8, Moscow 119881, Russian Federation |
| |
| Abstract: | A fundamentally new recognition method of bio-objects (e.g., cancer cells as the most important case of them) that escape the immune system supervision control is suggested. It is proposed to use a unified complex consisting of several molecular groups (e.g., antibodies or their fragments) bound with each other. Binding targets are localized on the surface of this bio-object. The choice of the targets is determined by antigen profiling being expressed on the surface of these bio-objects. The recognition efficiency appears to be notably higher than in a situation when molecular groups do not form a unified complex and act separately. |
| |
| Keywords: | Modern principles of multitarget anticancer therapy Surface signalling molecules Tumour profiling Tumour signature Nano-device |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
