Neurotransmitter amino acid—oxobenzo[f]benzopyran conjugates: synthesis and photorelease studies |
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Authors: | Maria JG Fernandes |
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Institution: | Centro de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal |
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Abstract: | A series of fluorescent conjugates of neurotransmitter amino acids, such as β-alanine, tyrosine, 3,4-dihydroxyphenylalanine (DOPA) and glutamic acid, were prepared by reaction with a suitable fluorophore, namely 1-chloromethyl-9-methoxy-3-oxo-3H-benzof]benzopyran. The photophysical properties of the resulting ester bioconjugates were evaluated as well as the stability to photolysis at different wavelengths of irradiation (250, 300, 350 and 419 nm). |
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Keywords: | Oxobenzobenzopyran Benzocoumarin Neurotransmitters Amino acids Photolysis |
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