Synthesis and characterization of 5-substituted 8-hydroxyquinoline derivatives and their metal complexes |
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| Authors: | Lihua Li |
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| Affiliation: | a Department of Chemistry, The Hong Kong University of Science & Technology, Clear Water Bay, Hong Kong, China
b Department of Chemistry, Brandeis University, Waltham, MA 02454, USA |
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| Abstract: | 5-Aminomethyl-8-hydroxyquinoline (QN) was synthesized as a scaffold to generate dimers, trimers, and tetramer metalloquinolates. Starting from QN, a series of 5-substituted 8-hydroxyquinoline derivatives conjugated with small bioactive molecules were synthesized. Absorption and emission spectra indicate that these QN derivatives chelate well with metal ions, which may serve as a new platform to explore the applications of metalloquinolates for a variety of potential applications. |
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| Keywords: | 8-Hydroxyquinoline Metalloquinolate Absorption Emission |
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