Rh-catalyzed novel α-fluoroalkylation of α,β-unsaturated ketones and its mechanism |
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| Authors: | Kazuyuki Sato |
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| Institution: | Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan |
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| Abstract: | Treatment of α,β-unsaturated ketones and fluoroalkyl halides with Et2Zn in the presence of RhCl(PPh3)3 gave novel reductive fluoroalkylation products at the α-position of α,β-unsaturated ketones in moderate to good yields. The rhodium hydride complex derived from Et2Zn and Rh catalyst seems to have played an important role in this reaction. |
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| Keywords: | Fluorine Fluoroalkyl Rhodium α β-Unsaturated ketone α-Position |
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