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A NEW N-NITROSO COMPOUND, N-2-METHYLPROPYL-N-1-METHYLACE-TONYL-NITROSAMINE, IN MOLDY MILLET AND WHEAT FLOUR
作者姓名:季川  徐致祥  李铭新  李国玉  李金兰
作者单位:Department of Chemical Etiology and Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences,Beijing,Department of Chemical Etiology and Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences,Beijing,Department of Chemical Etiology and Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences,Beijing,Department of Chemical Etiology and Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences,Beijing,Department of Chemical Etiology and Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences,Beijing
摘    要:A new N-nitroso compound, N-2-methylpropyl-N-1-methylacetonyl-nitrosamine(MAMPNA), was found in millet and wheat flour inoculated with Fusarium moniliformeSheldon, a common species of fungi occurring in foods in Linxian County, after 8-day incu-bation and an addition of a small amount of NaNO_2. The compound has been identified byGC-MS and confirmed by synthesized MAMPNA. The present paper reports the isolationand detection of MAMPNA in moldy foods, and discusses the role of the fungus in processesof nitrosamine formation and possible biosynthetic approach of the new compound.

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