NMR study of bis-4-fluoroaniline Schiff base of gossypol

The title compound has been prepared. Using ¹H NMR, ¹³C NMR and selected decoupling method, the compound is shown in the keto-form. DNMR method was used to investigated the exchange between NH in the title compound and water in DMSO-d₆. The rate process was calculated by complete line shape analysis method and activation parameters ΔH≠, ΔG≠ and ΔS≠ were found to be 8.4±0.5 kcalmol^?1, 16.9±0.2 kcalmol^?1 and ?26.9±1.5 calmol^?1 k^?1 respectively.