Hétérocycles à fonction quinone. 7. Benzo[f]quinazolinediones-7,10 à action antitumorale potentielle |
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Authors: | H l ne Parrot-Lopez,Jean-Michel Delacotte,Jean Renault,Suzanne Cros |
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Affiliation: | Hélène Parrot-Lopez,Jean-Michel Delacotte,Jean Renault,Suzanne Cros |
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Abstract: | Few benzo[f]quinazoline-7,10-diones 4a-c are prepared by oxidation, with potassium nitrosodisulfonate, of the corresponding benzo[f]quinazolinamines, made by reduction of the nitro analogues which were obtained from 8-methoxybenzo[f]quinazolin-1(2H)-one. The compound 4a shows an interesting cytotoxicity. |
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