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Hétérocycles à fonction quinone. 7. Benzo[f]quinazolinediones-7,10 à action antitumorale potentielle
Authors:Hlne Parrot-Lopez  Jean-Michel Delacotte  Jean Renault  Suzanne Cros
Institution:Hélène Parrot-Lopez,Jean-Michel Delacotte,Jean Renault,Suzanne Cros
Abstract:Few benzof]quinazoline-7,10-diones 4a-c are prepared by oxidation, with potassium nitrosodisulfonate, of the corresponding benzof]quinazolinamines, made by reduction of the nitro analogues which were obtained from 8-methoxybenzof]quinazolin-1(2H)-one. The compound 4a shows an interesting cytotoxicity.
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