Hétérocycles à fonction quinone. 7. Benzo[f]quinazolinediones-7,10 à action antitumorale potentielle |
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Authors: | Hlne Parrot-Lopez Jean-Michel Delacotte Jean Renault Suzanne Cros |
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Institution: | Hélène Parrot-Lopez,Jean-Michel Delacotte,Jean Renault,Suzanne Cros |
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Abstract: | Few benzof]quinazoline-7,10-diones 4a-c are prepared by oxidation, with potassium nitrosodisulfonate, of the corresponding benzof]quinazolinamines, made by reduction of the nitro analogues which were obtained from 8-methoxybenzof]quinazolin-1(2H)-one. The compound 4a shows an interesting cytotoxicity. |
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