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Reaction of 2-acetyltetralone with some esters of benzoic acid
Authors:A. Arcoleo  M. Gottuso  G. Giammona  G. Fontana  G. Abbate
Abstract:In order to investigate the pharmacological screening of a number of pyran-4-ones their synthesis by cyclization with sulphuric acid of the corresponding 1,3,5-triketones has been carried out with high yields. In the course of preparation of the latter the reaction of 2-acetyltetralone with some esters of benzoic acid derivatives has been studied and in particular, for a number of them, an interesting nucleophilic substitution of a chlorine atom with an alkoxy group on a benzenic nucleus has been evidenced.
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