A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB) |
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| Authors: | Yim Yeong Shin Choi Jin-sil Kim Gun Tae Kim Chul Hoon Shin Tae-Hyun Kim Dong Goo Cheon Jinwoo |
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| Institution: | Department of Pharmacology, Yonsei University, College of Medicine, Seoul 120-752, Korea. |
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| Abstract: | This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood-brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests. |
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