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The role of lipophilicity in transmembrane anion transport
Authors:Saggiomo Vittorio  Otto Sijbren  Marques Igor  Félix Vítor  Torroba Tomás  Quesada Roberto
Affiliation:Centre for Systems Chemistry, Stratingh Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
Abstract:The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.
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