Synthesis of 2-spiro-(1,2-dihydroperimid-2-yl)-5,5-dialkyl-2,3,5,6-tetrahydropyrrolo[2,1-a]-isoquinolin-3-ones |
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| Authors: | O V Surikova Z G Aliev A G Mikhailovskii |
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| Institution: | (1) Perm State Pharmaceutical Academy, Perm, 614990, Russia;(2) Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, 142432 Moscow region, Russia |
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| Abstract: | 2,3-Dioxpyrrolo2,1-a]isoquinolines react with 1,8-naphthalenediamine in 2-propanol in the presence of p-toluenesulfonic acid to give 2-spiro-(1,2-dihydroperimid-2-yl)-5,5-dialkyl-2,3,5,6-tetrahydro-pyrrolo2,1-a]isoquinolin-3-ones whose structure was confirmed by X-ray analysis.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1849–1854, December, 2008. |
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| Keywords: | 5 5-dialkyl-2 3-dioxopyrrolo[2 1-a]isoquinolines 1 8-naphthalenediamine 2-spiro-(1 2-di-hydroperimid-2-yl)-5 5-dialkyl-2 3 5 6-tetrahydropyrrolo[2 1-a]isoquinolin-3-ones acid catalysis X-ray structural analysis |
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