Modification of AFM Tips for Facilitating Picking-up of Nanoparticles |
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Authors: | WANG Peng YANG Hai-Jun WANG Hua-Bin LI Hai WANG Xin-Yan WANG Ying LÜ Jun-Hong LI Bin ZHANG Yi HU Jun |
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Institution: | Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800Bio-X Life Science Research Center, College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240Graduate School of the Chinese Academy of Sciences, Beijing 100049 |
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Abstract: | The radius of atomic force microscope (AFM) tip is a key factor that influences nonspecific interactions between AFM tip and nanoparticles. Generally, a tip with larger radius contributes to a higher efficiency of picking up nanoparticles. We provide two methods for modifying the AFM tip: one is to wear a tip apex on a solid substrate and the other is to coat a tip with poly (dimethylsiloxane) (PDMS). Both the approaches can enhance the adhesion force between the tip and nanoparticles by increasing tip radius. The experimental results show that a modified tip, compared to an unmodified one, achieves six-fold efficiency improvement in the capture of targeted colloidal gold nanoparticles. |
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Keywords: | 07 79 Lh 81 07 Lk |
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