Regioselective carbolithiation of o-amino-(E)-stilbenes: cascade route to the quinoline scaffold |
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| Authors: | Hogan Anne-Marie L O'Shea Donal F |
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| Institution: | Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland. |
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| Abstract: | reaction: see text] The regioselective carbolithiation of substituted ortho-amino-(E)-stilbenes can be exploited to initiate cascade reaction sequences that can be utilized as new routes to substituted 3,4-dihydro-1H-quinolin-2-ones, 1,2,3,4-tetrahydroquinolines, 1,4-dihydroquinolines, and quinolines. |
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