Radio TLC in quality control and development of radiopharmaceuticals |
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| Authors: | E. Gattavecchia D. Tonelli A. Breccia A. Fini E. Ferri |
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| Affiliation: | (1) Dipartimento di Chimica Industriale e dei Materiali, Università di Bologna, Viale Risorgimento 4, I-40136 Bologna, (Italy);(2) Istituto di Scienze Chimiche, Università di Bologna, Via San Donato 15, I-40127 Bologna, (Italy) |
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| Abstract: | Radio TLC has been used for determining the radiochemical purity and composition of two99mTc-radiopharmaceuticals, available as kits and commonly used for diagnostic imaging. Moreover, the same technique has been applied to detect impurities which decrease the specific activity of131I-derivatized dermatan sulfate, a new potential radiopharmaceutical, and for establishing the best labeling conditions. |
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