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新型显色基质法鲎试验对肺部革兰氏阴性菌感染患者的诊断意义
引用本文:钟定,覃寿明,许辉,张学荣,舒雨雁.新型显色基质法鲎试验对肺部革兰氏阴性菌感染患者的诊断意义[J].广西科学,1996,3(1):60-61,70.
作者姓名:钟定  覃寿明  许辉  张学荣  舒雨雁
作者单位:广西医科大学第一附属医院呼吸内科,广西医科大学蛇毒研究所
摘    要:应用新型显色基质法鲎试验(NCLA)测定41例肺部革兰阴性(G^-)细菌感染患者)G组);32例肺部非革兰氏阴性细菌感染患者(非G组);42例无细菌感染的肺病患者(无感染组)的血浆内毒素浓度、并与100例健康者(对照)比较,G组血浆内毒素水平明显高于对照组,非G组及无感染组(P均〈0.01)。提示新型显色基质法鲎试验有助于肺部G细菌感染作出快速,灵敏的诊断。

关 键 词:鲎试验  内毒素  肺炎  革兰氏阴性细菌  显色基质法
收稿时间:1995/4/8 0:00:00

Diagnostic Significance of New Chromogenic Limulus Assay in Patients with Pulmonary GRAM-Negative Bacterial Infection
Zhong Ding,Qin Shouming,Xu Hui,Zhang Xuerong and Shu Yuyan.Diagnostic Significance of New Chromogenic Limulus Assay in Patients with Pulmonary GRAM-Negative Bacterial Infection[J].Guangxi Sciences,1996,3(1):60-61,70.
Authors:Zhong Ding  Qin Shouming  Xu Hui  Zhang Xuerong and Shu Yuyan
Institution:Department of Respirato ry, The First Affiliated Hospital, Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021,Department of Respirato ry, The First Affiliated Hospital, Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021,Department of Respirato ry, The First Affiliated Hospital, Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021,The Snake Venom Rosearch Institute of Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021 and The Snake Venom Rosearch Institute of Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021
Abstract:The concentration of plasma endotoxin in 41 patients with pulmonary gram-negative (G-)bacterial infection (G-group), 32 patients with pulmonary non-G- bacterial infection (non G- group),42 patients without pulmonary bacterial infection (non infection group) were measured by the New Chromogenic Limulus Assay (NCLA), and compared with a control group of 100 normal cases. The concentration of plasma endotoxin in G- group was significantly higher than those of the control group.non G- group and non infection group (all P<0.01). The results showed that NCLA was a quick.sensitive and useful method for the diagnosis of pulmonary G- bacterial infection.
Keywords:limulus assay  endotoxin  pneumonia  gram-negative bacterum
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