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Ligand‐Controlled Regiodivergent Copper‐Catalyzed Alkylboration of Alkenes |
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| Authors: | Wei Su Dr. Tian‐Jun Gong Xi Lu Meng‐Yu Xu Chu‐Guo Yu Zheng‐Yang Xu Prof. Hai‐Zhu Yu Prof. Bin Xiao Prof. Yao Fu |
| Affiliation: | iChEM, CAS Key Laboratory of Urban Pollutant Conversion, Anhui Province Key Laboratory of Biomass Clean Energy, Department of Chemistry, University of Science and Technology of China, Hefei 230026 (China) |
| Abstract: | A novel copper‐catalyzed regiodivergent alkylboration of alkenes with bis(pinacolato)diboron and alkyl halides has been developed. The regioselectivity of the alkylboration was controlled by subtle differences in the ligand structure. The reaction thus enables the practical, regiodivergent synthesis of two different alkyl boronic esters with complex structures from a single alkene. |
| Keywords: | copper cross‐coupling difunctionalization homogeneous catalysis synthetic methods |