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Facile Enzymatic Synthesis of Ketoses |
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| Authors: | Liuqing Wen Kenneth Huang Mohui Wei Dr Jeffrey Meisner Dr Yunpeng Liu Kristina Garner Lanlan Zang Xuan Wang Xu Li Dr Junqiang Fang Dr Houcheng Zhang Prof?Dr Peng George Wang |
| Institution: | 1. Department of Chemistry and Center for Therapeutics and Diagnostics, Georgia State University, Atlanta, GA 30303 (USA);2. Current Address: Division of Pulmonary, Allergy and Immunology, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322 (USA);3. National Glycoengineering Research Center, Shandong University, Jinan 250100 (China) |
| Abstract: | Studies of rare ketoses have been hampered by a lack of efficient preparation methods. A convenient, efficient, and cost‐effective platform for the facile synthesis of ketoses is described. This method enables the preparation of difficult‐to‐access ketopentoses and ketohexoses from common and inexpensive starting materials with high yield and purity and without the need for a tedious isomer separation step. |
| Keywords: | enzymatic synthesis ketoses one‐pot reactions phosphorylation synthetic methods |