All‐Carbon [3+3] Oxidative Annulations of 1,3‐Enynes by Rhodium(III)‐Catalyzed CH Functionalization and 1,4‐Migration |
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| Authors: | Dr. David J. Burns Dr. Daniel Best Dr. Martin D. Wieczysty Prof. Hon Wai Lam |
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| Affiliation: | 1. School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD (UK);2. EaStCHEM, School of Chemistry, University of Edinburgh, Joseph Black Building, The King's Buildings, David Brewster Road, Edinburgh EH9 3FJ (UK) |
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| Abstract: | 1,3‐Enynes containing allylic hydrogens cis to the alkyne function as three‐carbon components in rhodium(III)‐catalyzed, all‐carbon [3+3] oxidative annulations to produce spirodialins. The proposed mechanism of these reactions involves the alkenyl‐to‐allyl 1,4‐rhodium(III) migration. |
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| Keywords: | allylation C H activation enynes homogeneous catalysis rhodium |
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