Catalytic Silylations of Alcohols: Turning Simple Protecting‐Group Strategies into Powerful Enantioselective Synthetic Methods |
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| Authors: | Prof?Dr Li‐Wen Xu Yun Chen Prof?Dr Yixin Lu |
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| Institution: | 1. Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, No. 1378, Wenyi West Road, Hangzhou, 311121 (P.?R. China);2. Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education (MOE), and School of Chemistry and Chemical Engineering, Shaanxi Normal University, No. 620, West Chang'an Avenue, Xi'an 710119 (P.?R. China);3. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543 (Republic of Singapore) |
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| Abstract: | In recent years, remarkable progress has been made in the enantioselective silylation of alcohols. Owing to the successful site‐ and stereoselective functionalization of hydroxy groups, silyl ether formations have evolved from being a simple reaction for functional‐group protection into a powerful enantioselective process. In this Minireview, we highlight important recent findings in this emerging field. |
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| Keywords: | asymmetric catalysis desymmetrization enantioselectivity kinetic resolution silylation |
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