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| 碲化镉量子点作为探针研究核黄素与鲑鱼精DNA的相互作用 | |
| 引用本文： | 张渝阳,李荧荧,赵琨,赵玲,臧树良.碲化镉量子点作为探针研究核黄素与鲑鱼精DNA的相互作用[J].化学学报,2011,69(16):1951-1956. |
| 作者姓名： | 张渝阳 李荧荧 赵琨 赵玲 臧树良 |
| 作者单位： | 1. 辽宁大学化学院,沈阳110036／辽宁大学稀散元素研究所,沈阳110036 2. 辽宁大学化学院,沈阳,110036 3. 沈阳药科大学药学院,沈阳110016／辽宁大学稀散元素研究所,沈阳110036 |
| 基金项目： | 国家自然科学基金(No.21071073); 辽宁大学青年研究基金(No.2009LDQN24)资助项目 |
| 摘 要： | 在水相中合成了巯基丙酸包覆的CdTe量子点（CdTe QDs）,以CdTe QDs作为探针,在pH 7.25 Britton-Robinson（B-R）缓冲溶液中,应用荧光光谱法、紫外吸收光谱法,对核黄素（RF）与鲑鱼精DNA作用方式进行了研究.RF与DNA作用时,使荧光强度降低,紫外吸收明显减色,通过盐效应实验和DN... |
| 关 键 词： | 量子点 核黄素 鲑鱼精DNA 荧光光谱 嵌插作用 |
CdTe Quantum Dots as a Probe for Interaction between Salmon Sperm DNA and Riboflavin |
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| Zhang,Yuyang,a,c Li,Yingyinga Zhao,Kunb,c Zhao,Linga Zang,Shulianga,c.CdTe Quantum Dots as a Probe for Interaction between Salmon Sperm DNA and Riboflavin[J].Acta Chimica Sinica,2011,69(16):1951-1956. | |
| Authors: | Zhang Yuyang a c Li Yingyinga Zhao Kunb c Zhao Linga Zang Shulianga c |
| Institution: | Zhang,Yuyang,a,c Li,Yingyinga Zhao,Kunb,c Zhao,Linga Zang,Shulianga,c(a College of Chemistry,Liaoning University,Shenyang 110036)(b School of Pharmacy,Shengyang Pharmaceutical University,Shenyang 110016)(c Institute of Rare and Scattered Elements,Shenyang 110036) |
| Abstract: | The water-soluble CdTe quantum dots(QDs) were synthesized using mercaptopropionic acid as stabilizer.The interaction of riboflavin(RF) with salmon sperm DNA was investigated using UV and fluorescent spectra by employing CdTe QDs as a fluorescence probe in pH 7.25 Britton-Robinson(B-R) buffer solution.Decreased fluorescence and hypochromism of UV spectra were observed as RF interaction with DNA.The interaction of riboflavin with DNA has also been studied through methods of salt effect and thermal denaturatio... |
| Keywords: | CdTe quantum dots riboflavin salmon sperm DNA fluorescent spectrum intercalation |
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