Tandem one pot synthesis of 1,5-benzodiazocine-2-one by isocyanide based Ugi multicomponent reaction |
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| Authors: | Goutam KulsiAbhijit Ghorai Partha Chattopadhyay |
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| Affiliation: | Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700 032, India |
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| Abstract: | We have developed an efficient one-pot, two-step reaction protocol for the synthesis of eight-membered 1,5-benzodiazocine-2-ones by Ugi four-center three-component coupling reaction (U-4C-3CR) and subsequent reductive cyclization using Fe/NH4Cl in protic solvent. |
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| Keywords: | Ugi reaction IMCR Benzodiazocine Fe/NH4Cl Heterocycles |
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