P,N-Type benzimidazolyl phosphine ligands for the palladium-catalyzed Suzuki coupling of potassium aryltrifluoroborates and aryl chlorides |
| |
| Authors: | Shun Man WongChau Ming So Kin Ho ChungChi Him Luk Chak Po LauFuk Yee Kwong |
| |
| Institution: | State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong |
| |
| Abstract: | This study describes the efficacy of P,N-type benzimidazolyl phosphine ligands, which can be easily synthesized from commercially available and inexpensive starting materials. The application of this ligand array in palladium-catalyzed Suzuki-Miyaura coupling reaction of aryl chlorides with potassium aryltrifluoroborates is described. The air stable benzimidazolyl phosphines in combination with a palladium metal precursor provides highly effective catalysts for the Suzuki-Miyaura coupling of unactivated aryl chlorides and can achieve a catalyst loading of only 0.05 mol %. |
| |
| Keywords: | Suzuki coupling P N-Type ligand Phosphine Trifluoroborate Palladium |
| 本文献已被 ScienceDirect 等数据库收录！ |
