| A Paleogenomic Algorithm for Reconstruction of Ancient Operons from Complete Microbial Genome Sequences |
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| 作者姓名： | WANGYu-hong LIWei FANGXue-xun JohnP.Rose WANGBi-Cheng LINDa-wei |
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| 作者单位： | [1]DepartmentofMolecularBiology,JilinUniversity,Changchun130023,P.R.China [2]SoutheastCollaboratoryforStructuralGenomics,DepartmentofBiochemistryandMolecularBiology,UniversityofGeorgia,Athens,GA30602,Greece |
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| 基金项目： | Supported by the National Natural Science Foundation of China(No.30 2 4 0 0 16 ) and the NIGMS Protein Structure Ini-tiative(No.GM0 6 2 4 0 7) |
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| 摘 要： | Operons, or co-transcribed and co-regulated contiguous sets of genes, in microbial genomes are poorly conserved across different genomes due to gene fusion, deletion, duplication and other genome shuffling processes. The currently available genomes are the results of numerous reshuf-
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| 关 键 词： | 操纵子 古微生物 整体最优化 基因组 运算法则 基因序列 |
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