Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents |
| |
| Authors: | Endo Kohei Hamada Daisuke Yakeishi Sayuri Ogawa Mika Shibata Takanori |
| |
| Institution: | Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa 920-1192, Japan. kendo@se.kanazawa-u.ac.jp |
| |
| Abstract: | Multinuclear Cu/Zn complex-catalyzed efficient asymmetric conjugate addition of organozinc reagents to acyclic and cyclic enones has been developed in the presence of a wide variety of regioisomeric chiral diols bearing phosphorus moieties as ligands. The regioisomeric SPINOL-PHOS ligands based on a SPINOL architecture showed an unexpected inversion of stereoselectivity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
