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Three New Pregnane Glycosides from Marsdenia tinctoria
Authors:Zhu‐Lin Gao  Hong‐Ping He  Ying‐Tong Di  Xin Fang  Chun‐Shun Li  Qiang Zhang  Pei‐Ji Zhao  Shun‐Lin Li  Xiao‐Jiang Hao
Institution:1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.?R. China, (phone: +86‐871‐5223263;2. fax: +86‐871‐5219684);3. Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan 650091, P.?R. China;4. Graduate University of the Chinese Academy of Sciences, Beijing 100039, P.?R. China
Abstract:Three new pregnane glycosides, tinctorosides A–C ( 1 – 3 , resp.), together with one known pregnane glycoside, stephanoside B ( 4 ), were isolated from the stems of Marsdenia tinctoria R. Br . (Asclepiadaceae). Their structures were elucidated by extensive spectral methods, especially 2D‐NMR experiments (1H,1H‐COSY, HSQC, HMBC, TOCSY, HSQC‐TOCSY, and ROESY), and chemical evidence.
Keywords:Marsdenia tinctoria  Glycosides  Pregnane glycosides  Tinctorosides A       C  Stephanoside B
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