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Three Unusual New Sesquiterpenes from Alpinia oxyphylla
Authors:Jun‐Ju Xu  Ning‐Hua Tan  Yi‐Shan Chen  Xu‐Lin Pan  Guang‐Zhi Zeng  Hong‐Jin Han  Chang‐Jiu Ji  Mei‐Ju Zhu
Institution:1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.?R. China, (phone: +86‐871‐5223800;2. fax: +86‐871‐5223800);3. Graduate University of the Chinese Academy of Sciences, Beijing 100049, P.?R. China
Abstract:Two new norcadinene sesquiterpenes oxyphyllones C and D ( 1 and 2 , resp.), and one new 1,10‐secoguaiane sesquiterpene, (+)‐mandassidion ( 3 ), together with two known compounds, oxyphyllenodiol B ( 4 ) and (1R,2R)‐p‐menth‐3‐ene‐1,2‐diol ( 5 ), were isolated from the fruits of Alpinia oxyphylla. Their structures were determined on the basis of spectroscopic analysis, including 2D‐NMR spectroscopic techniques. Compounds 1, 2 , and 3 exhibited no cytotoxicity against three cancer cell lines.
Keywords:Alpinia oxyphylla  Sesquiterpenes  Norcadinene sesquiterpenes  1  10‐Secoguaiane sesquiterpenes  Oxyphyllones C and D
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