Facile Access to Benzothiazole‐Containing Pyrrolo[1,2‐a]quinolines and Pyrrolo[2,1‐a]isoquinolines via Nitrogen Ylides |
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| Authors: | Kamal M Dawood Eman A Ragab Nabila A Khedr |
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| Institution: | Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt |
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| Abstract: | Quinoline and isoquinoline react with 2‐(bromoacetyl)benzothiazole ( 1 ) in dry benzene to give the corresponding quinolinium and isoquinolinium salts 2 and 10 which undergo base‐mediated 3+2] 1,3‐dipolar cycloaddition with some acetylene and ethylene derivatives to give the corresponding benzothiazole‐containing pyrrolo1,2‐a]quinoline and pyrrolo2,1‐a]isoquinoline derivatives. |
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| Keywords: | Benzothiazoles Pyrrolo[1 2‐a]quinolines and pyrrolo[2 1‐a]isoquinolines Nitrogen ylides 1 3‐Dipolar cycloaddition |
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