Bidesmosidic Oleanane Saponins from Xerospermum noronhianum |
| |
| Authors: | Tan?Pei Jean Khozirah Shaari Christian Paetz Intan?Safinar Ismail Faridah Abas Nordin?H Lajis Viqar?Uddin Ahmad |
| |
| Institution: | 1. Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia (phone: +60?389466776;2. fax: +60?389435380);3. Max‐Planck‐Institute for Chemical Ecology, Hans‐Kn?ll‐Stra?e 8, DE‐07745 Jena;4. H.?E.?J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan |
| |
| Abstract: | Three new oleanane‐type triterpenoid saponins, 3‐O‐(α‐L ‐rhamnopyranosyl(1→2)‐β‐D ‐fucopyranosyl)‐28‐O‐{α‐L ‐rhamnopyranosyl(1→2)] β‐D ‐fucopyranosyl(1→6)]‐β‐D ‐glucopyranosyl} oleanolic acid ( 1 ), 3‐O‐α‐L ‐rhamnopyranosyl(1→3)‐β‐D ‐fucopyranosyl]‐28‐O‐α‐L ‐rhamnopyranosyl(1→4)‐β‐D ‐glucopyranosyl] oleanolic acid ( 2 ), and 3‐O‐{α‐L ‐rhamnopyranosyl(1→2)‐3′,4′‐diacetoxy‐β‐D ‐fucopyranosyl]}‐28‐O‐α‐L ‐rhamnopyranosyl(1→2)‐β‐D ‐glucopyranosyl] oleanolic acid ( 3 ) have been isolated from the stems of Xerospermum noronhianum. The structures of the saponins were determined as a series of bidesmosidic oleanane saponins based on spectral evidence. The anticholinesterase activity of the saponins 1 – 3 was also evaluated. |
| |
| Keywords: | Xerospermum noronhianum Triterpenoids Oleanolic acid Saponins |
|
|
