Synthesis of 6‐Bromocoumarins Using Tetrabutylammonium Tribromide as a Selective Brominating Agent and an Efficient Generator of HBr |
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| Authors: | Li‐Qiang Wu Chun‐Guang Yang Yan‐Fang Wu Li‐Min Yang |
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| Affiliation: | School of Pharmacy, Xinxiang Medical College, Xinxiang, Henan 453003, P. R. China |
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| Abstract: | A simple and efficient one‐pot synthesis of 6‐bromocoumarins was achieved in good yields via the three‐component reaction of phenols, 4‐substituted acetoacetate and tetrabutylammonium tribromide (TBATB) in CH2Cl2‐MeOH. |
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| Keywords: | 6‐Bromocoumarins Tetrabutylammonium tribromide Pechmann reaction |
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