Synthesis and Characterization of Novel Stilbene Derivatives with 1,3,4‐Oxadiazole Unit |
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| Authors: | Dao‐Hang He Yong‐Chuang Zhu Zhuo‐Ru Yang Ai‐Xi Hu |
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| Affiliation: | 1. College of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China;2. College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China |
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| Abstract: | Four novel stilbene derivatives containing 1,3,4‐oxadiazole unit have been synthesized in four steps with overall yields (27～35%). The synthetic route involved one‐step installation of 2,5‐di‐p‐tolyl‐1,3,4‐oxadiazol via the direct coupling of p‐toluic acid with hydrazine hydrate promoted by PPA , benzylic bromination, conventional phosphonate formation, and Wittig‐Horner olefination. |
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| Keywords: | Stilbene derivatives 1,3,4‐Oxadiazole unit Synthesis |
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