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New Derivatives of Ascomycin with Modifications in the Amino Acid Region – Synthesis and Biological Activities,and X‐Ray Crystal Structure of 5,6‐Dehydroascomycin
Authors:Murty?A?R?C Bulusu  Peter Waldstätten  Thomas Tricotet  Christophe Rochais  Andrea Steck  Markus Bacher  Gerhard Schulz  Josef?G Meingassner  Peter Hiestand  Gerhard Zenke  Walter Schuler  Trixie Wagner
Institution:1. Novartis Institutes for BioMedical Research GmbH & Co KG, Brunnerstrasse 59, A‐1235 Vienna;2. Current address: Nabriva Therapeutics AG, Leberstrasse 20, A‐1112 Vienna, (phone: +43‐1‐740931213;3. fax: +43‐1‐74093 1900);4. Current address: Bruker Analytical Services Austria (Bruker Austria GmbH), Leberstrasse 20, A‐1112 Vienna.;5. Novartis Institutes for BioMedical Research, Lichtstrasse 35, CH‐4002 Basle
Abstract:
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Keywords:Ascomycin  Photolysis  X‐Ray crystallography  5  6‐Dehydroascomycin  Dermatitis  Immunomodulation  Macrolides  Macrophilin
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