Electrochemical Behavior of Apigenin at a Glassy Carbon Electrode and its Analytical Application

The electrochemical behavior of the antitumor herbal drug apigenin was studied in 0.1 mol L^?1 B‐R buffer solutions (50% ethanol, pH 3.0) by cyclic voltammetry (CV) at a glassy carbon electrode. In CV, two oxidation peaks (P₁ and P₂) with E_p1 = 1.03V and E_p2 = 1.23 V appeared at a scan rate of 0.05 V s^?1, and a new electroanalytical method for this herbal drug was established according to the oxidation peak P2. The peak currents have a linear relationship with apigenin concentration in a range from 9.0 × 10^?7 to 2.0 × 10^?5 mol L^?1. Using the established method, apigenin in a herbal drug was determined without pre‐separation with satisfactory results. Moreover, the electrode dynamics parameters were also investigated by electrochemical techniques and the possible electrode reaction mechanism was deduced.