[1] Benzofuro[2,3-d] pyridazines. VI. Etude des reactions de scission des acyltetrahydrobenzofuropyridazones |
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Authors: | Max Robba Michel Cugnon De Sevricourt Anne-Marie Godard |
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Abstract: | The cleavage of the pyridazine ring of the acyltetrahydro 1] benzofuro 2,3-d] pyridazones was carried out by hydrolysis, alcoholysis or aminolysis reactions and they affect the lactam 3,4-bond. They lead chiefly to benzofuran derivatives with acid, ester, amide or hydrazide groups in the 2-position and eventually an acylated methylhydrazine group in the 3-position. The cyclization reactions of 3-hydrazinomethylbenzofuran-2-carboxylic acid and its derivatives or ethyl 3-bromome thylbenzofuran-2-carboxylate affords tetrahydrobenzofuropyridazones. The nmr spectra were studied. |
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