| 波段三维ESR成像系统的研制（Ⅴ）——灵敏度与分辨率实验及系统总性能指标 |
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| 引用本文： | 吴可,丛建波,张清俊,先宏,王长振,孙存普,郑莹光,许静,董凤霞,沈尔中,徐玉书.波段三维ESR成像系统的研制（Ⅴ）——灵敏度与分辨率实验及系统总性能指标[J].波谱学杂志,2004,21(2):159-164. |
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| 作者姓名： | 吴可 丛建波 张清俊 先宏 王长振 孙存普 郑莹光 许静 董凤霞 沈尔中 徐玉书 |
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| 作者单位： | 1. 军事医学科学院 放射医学研究所，国家生物医学分析中心自由基与顺磁共振实验室，北京 100850; 2.吉林大学 分析测试中心, 吉林 长春 130022 |
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| 摘 要： | 实验确定了自行研制的L波段三维电子自旋共振成像（3D-ESRI）系统的检测灵敏度及成像分辨率指标. 用Tempo水溶液模型测量灵敏度结果表明： 样品体积为10 mm, 高30 mm，测量浓度1×10-4 mol/L水溶液的信噪比为S/N=4∶1；加梯度磁场后，样品浓度需>5×10-4 mol/L，样品体积为19 mm, 高30 mm时，获得的投影谱的信噪比可满足图像重建的需要. 用DPPH固体样品确定的成像分辨率结果<1 mm. 文中还对ESRI系统的
各项总体性能做了归纳总结.
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| 关 键 词： | 电子自旋共振 3D-ESR成像 灵敏度 分辨率 性能指标 |
| 文章编号： | 1000-4556(2004)02-0159-06 |
| 收稿时间： | 2003-07-24 |
| 修稿时间： | 2003年7月24日 |
DEVELOPMENT OF L BAND THREE DIMENSIONAL ESR IMAGING SYSTEM(Ⅴ)--System Configuration and Performance Evaluation |
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| WU Ke,CONG Jian-bo,ZHANG Qing-jun,XIAN Hong,WANG Chang-zhen,SUN Cun-pu.DEVELOPMENT OF L BAND THREE DIMENSIONAL ESR IMAGING SYSTEM(Ⅴ)--System Configuration and Performance Evaluation[J].Chinese Journal of Magnetic Resonance,2004,21(2):159-164. |
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| Authors: | WU Ke CONG Jian-bo ZHANG Qing-jun XIAN Hong WANG Chang-zhen SUN Cun-pu |
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| Institution: | 1.Institute of Radiation Medicine, Academy of Military Medical Science, National Center of Biomedical Analgsis, FR&ESR Lab, Beijing 100850, China; 2.Analytic and Measure Center, Jilin University, Changchun 130022, China |
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| Abstract: | The detection sensitivity and the achievable spatial resolution of a newly developed L-band three-dimensional ESR imaging system were evaluated. Thedetection sensitivity was measured using a group of samples of aqueous Tempo solution. A signal to noise ratio (S/N) of about 4∶1 was obtained on a cylindric al sample with diameter of 10 mm and height of 30 mm, which corresponds to the minimum detectable concentration of 1×10-4 mol/L. To obtain projections with sufficient S/N for imaging, a higher concentration of more than 5×10-4 mol/L and a largersample size (diameter ofφ19 mm and height of 30 mm) was needed. Measured on solid DPPH samples, the spatial resolution of imaging can reach about 1 mm. The general performance features of the ESRI system were also discussed in the paper. |
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| Keywords: | ESR 3D-ESRI sensitivity resolution performance feature |
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