Palladium‐Catalyzed Insertion of an Allene into an Aminal: Aminomethylamination of Allenes by C?N Bond Activation |
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Authors: | Jianhua Hu Yinjun Xie Hanmin Huang |
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Abstract: | A new and atom‐economic palladium‐catalyzed aminomethylamination of allenes with aminals by C N bond activation is described. This direct and operationally simple method provides a fundamentally novel approach for the synthesis of 1,3‐diamines. Mechanistic studies suggest that a unique cationic π‐allylpalladium complex containing an aminomethyl moiety is generated as a key intermediate through the carbopalladation of the allene with a cyclometalated palladium–alkyl species. |
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Keywords: | Allene Aminale C‐N‐Aktivierung Diamine Palladium |
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