| Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate |
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| 作者姓名： | YUAN Cheng-Ye ZHAI Hai-Xiao WENG Guan-HongShanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai China |
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| 作者单位： | YUAN，Cheng-Ye ZHAI，Hai-Xiao WENG，Guan-HongShanghai Institute of Organic Chemistry，Chinese Academy of Sciences，Shanghai 200032，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China。 |
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| 摘 要： | A new synthetic approach to 1,4,6-tri-O-benzyl myo-inositol was described on the basis of the regioselective benzylation of 1,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol, subsequent acid hydrolysis, phosphorylation with tetrabenazylpyrophosphate and appropriate deprotec-tion.
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Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate |
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| YUAN,Cheng-Ye ZHAI,Hai-Xiao WENG,Guan-HongShanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai ,China.Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate[J].Chinese Journal of Chemistry,1994,12(2):174-178. |
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| Authors: | YUAN Cheng-Ye ZHAI Hai-Xiao WENG Guan-Hong |
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| Institution: | YUAN,Cheng-Ye ZHAI,Hai-Xiao WENG,Guan-HongShanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China |
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| Abstract: | A new synthetic approach to 1,4,6-tri-O-benzyl myo-inositol was described on the basis of the regioselective benzylation of 1,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol, subsequent acid hydrolysis, phosphorylation with tetrabenazylpyrophosphate and appropriate deprotec-tion. |
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| Keywords: | myo-Inositol synthesis regioselective benzylation |
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